Study of the adsorption capacity of pharmaceutical enterosorbents

Project leaderPh.D. in ChemistryAssociate Professor, Student, Student, Student, Student

Description

The enterosorption method is actively used in the treatment of acute and chronic intoxications of various origins, which are increasingly common in medical practice. Understanding the adsorption activity of enterosorbents allows for a more reasonable choice of treatment regimens and drugs, which, in turn, contributes to more effective therapy results. The results of the study make it possible to give an objective assessment of the effectiveness of existing drugs and optimize the choice of sorbent for specific clinical situations

Key objectives

Study of physico-chemical properties of pharmaceutical enterosorbents of various compositions
Conducting a comparative analysis of the morphology, structure, and surface composition of selected enterosorbents using optical microscopy and IR spectroscopy
Conducting a qualitative analysis of the adsorption activity of selected enterosorbents by visual colorimetry with various low molecular weight toxins
Carrying out a quantitative analysis of the adsorption activity of selected drugs by acid-base titration, reverse titrimetry and photoelectrocolorimetry

Publications

Yankova V.Gr., Udyanskaya I.L. N., T. Slonskaya.Kn., Zhukova A.A., Grigorieva V.Yu., Gribanova S.V., K. Gryaznov.O., Kirichenko A.N., O. Plakhotnaya.N., Karpyn A.B. Research of the adsorption activity of an enterosorbent based on hydrolyzed lignin. Issues of practical pediatrics. 2022; 17(1): 150–156. DOI: 10.20953/1817-7646-2022-1-150-156

Conference presentations

Малышева Е., Жукова А., Изучение адсорбционных свойств аптечных энтеросорбентов на основе структурных компонентов древесины по отношению к продуктам метаболизма этанола. IV международная научно-практическая конференция молодых ученых «Фармация. Вызовы времени» Устный доклад. 12.12.2024
Muhammad Naeem, Diploma student, Zhukova Anna, PhD in chemistry, associate professor. “Adsorption Ability of Pharmacy Enterosorbents: «Smecta(France)», «Normasorb-Lacto»,and «Superum White Sorbent Forte»”. The 6 th China -Russian Symposium for young scholars in 2026
Amaliya Ledovaya, Anna Zhukova, Pharmacy enterosorbents based on lignin hydrolysed: properties investigation and comparison of its efficiency. Устный доклад. 13.02.2023 The 4-th China-Russia young scholars international symposium
Karolina Abdel-Kerim, Amaliya Ledovaya, Anna Zhukova, Tatiana Slonskaya. Enterosorbent based on lignin hydrolysed and lactulose: investigation of its combined effect. 6th pharmacy updates congress and 5th IpharmsAnnual conference. Winner in the category scientific hallmarks of the PU-2023. February 2023
Zhukova, Anna Alexandrovna. "Study of the activity of drugs based on hydrolyzed lignin "Lactofiltrum"and "Filtrum-STI". International Scientific and Practical Conference "Pediatrics and Pharmacy of the XXI century: problems and their solutions". Oral report. 18.11.2022 Samarkand